I do intent to provide specific horde ebuilds for kolab at a later point. Right now there are still too many bugs and problems when integrating these two.
But I guess that this would also result in having horde installed twice. Once as a library in /usr/share/php, once as a webapp that get's installed into /usr/share/webapps and that will be transferred with webapp-config to /var/www/kolab/htdocs/horde.
So I don't think that you really need to remove the current horde. They should not bite each other
